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Scholar Rock

Key Facts as at 30.09.2024

Company locationUSA
Size in % of securities0.6%
Size of stake in company2.7%
Market capitalizationUSD 600 mn

Sector

Neuromuscular disease

Main candidate

Apitegromab

Main indications

SMA type 2 and 3, immuno-oncology

About the company

Scholar Rock is a biotechnology company focused on developing monoclonal antibodies that are able to modulate growth factors with extraordinary selectivity. The company was founded in 2012 and is headquartered in Cambridge, Massachusetts, in the US. Scholar Rock has a technology platform based on the understanding of the extracellular activation of growth factors. The company develops antibodies to target the latent, inactive forms of growth factors to selectively and locally modulate growth factor activity within the tissue microenvironment. The lead asset, apitegromab, is an antibody targeting TGF-β currently in Phase III clinical development for Spinal Muscular Dystrophy Type 2 and 3 with data expected in late 2024.

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All comments as at December 31, 2023 or beginning of investment.

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